A. Overview: This README file provides instructions on how to load these *.mat files. 

Sectional fluorescent images that examined the effects of FUS on brain solute transport. 
There are four sets of *.mat files, (a) TxOA_FUS+.mat, (b) TxOA_FUS-.mat, (c) TxFITC_FUS+.mat, and (d) TxFITC_FUS-.mat.

File description
	TxOA_FUS*.mat: Sectional pictures from OA distribution, which were used for Figure 1E.
	TxFITC_FUS*.mat: sectional pictures from FITC-d distribution, which were used for Figure 1F.

FUS+ denotes the data obtained using FUS sonicaiton while FUS- denotes control, unsonicated condition. 

Once loaded into the Matlab, each *.mat file contains two data sets (in different cells):

1. Data: A cell array with n (number of animals) by m (number of slices, from caudal to rostral direction) dimensions. 
Each cell contains a matrix (sized 2760 by 4913) associated with a fluorescent brain image.
An empty cell indicates the sections in which no image data available (e.g., toward the end of cuts) or data was omitted due to vibratome artifacts.
The section corresponding to the intracortical injection site is at m = 19 for OA, and m = 15 for FITC-d. 

2. animals_ID: The non-sequential values indicate the animal's ID. 
OIC# and FIC# belong to the FUS- group, while OII# and FII# belong to the FUS+ group.


B. Additiona two *.mat file, named ClearOA_FUS+.mat and ClearOA_FUS-.mat constains the data pertaining to sectional fluorescent images that examined the effects of FUS on brain solute clerance/drainage.  

File description
	ClearOA_FUS*.mat: Sectional pictures from OA distribution, which were used for Figure 2E.

Once loaded into the Matlab, each *.mat file contains two data sets (in different cells):

1. Data: A cell array with n (number of animals) by m (number of slices, from caudal to rostral direction) dimensions. 
Each cell contains a matrix (sized 2760 by 4913) associated with a fluorescent brain image.
An empty cell indicates the sections in which no image data available (e.g., toward the end of cuts) or data was omitted due to vibratome artifacts.
The section corresponding to the intracortical injection site is at m = 21.

2. animals_ID: The non-sequential values indicate the animal's ID. 
LNC# belong to the FUS- group, while LNS# belong to the FUS+ group.